![]() Here, we report baseline data of our 52-week ongoing study. The relationships of MDS-UPDRS and PDQ-8 with the patient's clinical background and undertaken medical interventions were determined. The primary measurements were the Movement Disorder Society unified Parkinson's disease rating scale (MDS-UPDRS) part I and the Parkinson's Disease Questionnaire (PDQ-8). Electronic address: aimed to investigate the prevalence and severity of nonmotor symptoms (NMSs) and to identify factors affecting NMSs and the health-related quality of life of Japanese patients with Parkinson's disease (PD).Ī total of 1021 patients with PD who had one or more NMS and showed wearing-off under anti-parkinsonian treatment were enrolled from 35 medical centers in Japan for this observational study. Electronic address: 10 Department of Neurology, Kitano Hospital, The Tazuke Kofukai Medical Research Institute, 2-4-20 Ohgimachi, Kita-ku, Osaka 530-8480, Japan. Electronic address: 9 Brain and Mind Research Center, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8602, Japan. Electronic address: 8 Department of Neurology, Juntendo University School of Medicine 3-1-3 Hongo, Bunkyo-ku, Tokyo 113-8431, Japan. ![]() Electronic address: 7 Department of Neurology and Clinical Pharmacology, Ehime University Graduate School of Medicine, 454 Shizukawa, Tohon, Ehime 791-0295, Japan. ![]() Electronic address: 6 Department of Neurology, Faculty of Medicine, Fukuoka University, 3-1-1, Maidashi, Higashi-ku, Fukuoka City, 812-8582, Japan. Electronic address: 5 Department of Neurology, Okayama Kyokuto Hospital, 567-1 Kurata, Okayama, 703-8265, Japan. Electronic address: 4 Division of Biostatistics, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8575, Japan. Electronic address: 3 Division of Biostatistics, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8575, Japan. Electronic address: 2 Department of Neurology, Juntendo University School of Medicine 3-1-3 Hongo, Bunkyo-ku, Tokyo 113-8431, Japan. 1 Division of Neurology and Gerontology, Department of Internal Medicine, School of Medicine, Iwate Medical University, 19-1 Uchimaru, Morioka, Iwate 020-8505, Japan Department of Neurology and Movement Disorder Research, Research Institute for Brain and Blood Vessels-Akita, 6-10 Senshukubotamachi, Akita 010-0874, Japan. ![]() ![]() ![]()
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